Maybe I’m misreading the only plot that mentions dosing numbers anywhere. It looks like the largest dosing group is getting 3mg/kg/day. That’s a lot scaled up to a 100kg person (like 10x a normal gummy for example).
Maybe I’m misreading the only plot that mentions dosing numbers anywhere. It looks like the largest dosing group is getting 3mg/kg/day. That’s a lot scaled up to a 100kg person (like 10x a normal gummy for example).
But if the average is better, then we’re will clearly win by using it. I’m not following the logic of tracking the worst case scenarios as opposed to the average.
Just like all humans can do right now, right?
I never see any humans on the rode staring at their phone and driving like shit.
I get that people like to be stubborn about this but there are very real and intuitive reasons that decimals don’t make sense everywhere. Consider how intuitive telling time using “kiloseconds” and decimals might be.
The right tool needs to be used for the right job. I am a scientist. In the lab, metric is fantastic as it allows for precision recording and I don’t care about intuition.
It’s not a point of pride to use one system over another. For example, in America we use both systems in the right contexts. I am happily able to fluidly switch between what’s most appropriate for the situation. I get that context/code switching is generally difficult but I think it’s an overall value add.
If you don’t fight it and accept that imperial is designed with base 12 and not base 10, everything makes more sense. Measurements across all of imperial are to be cut into 12, 6, 4, 3, or 2.
Sometime base 12 works really nicely, especially outside of a lab, when you want to be able to have as many options for division easily as possible.
Just the American ones though, right? 🤣
Thanks this is a lot of great detail on the dosing mechanism that I think is really interesting. I love reading up on the experimental details and the actually components used to make these experiments work.
300mg of orally ingested THC spread out over 24 hours is about equivalent to consuming 1 typical candy/gummy every hour for 24 hours of the day. A reasonable or average or normal person would be uncomfortably high at these dosages. I also imagine the bioavailability of oral ingestion is less than the dosing mechanism you described although I’m not sure (is that getting taken up through the lymphatic system? How does it differ from oral ingestion or injection into the bloodstream?).
Fascinating stuff, thanks for sharing your knowledge.